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Febrifugine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Febrifugine图片
CAS NO:24159-07-7
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Febrifugine 是存在于常山的根和叶中的一种喹唑啉酮类生物碱,具有抗疟活性。
Cas No.24159-07-7
别名常山乙素
Canonical SMILESO=C1N(CC(C[C@H]2NCCC[C@@H]2O)=O)C=NC3=C1C=CC=C3
分子式C16H19N3O3
分子量301.34
溶解度DMF: 1.5 mg/ml,DMSO: 3.0 mg/ml,Ethanol: 0.1 mg/ml,PBS (pH 7.2): 2.5 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Febrifugine is a quinazolinone alkaloid found in the roots and leaves of Dichroa febrifuga, with antimalarial activity [1].

[1]. Herman JD, et al. The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs. Sci Transl Med. 2015 May 20;7(288):288ra77. [2]. McLaughlin NP, et al. The chemistry and biology of febrifugine and halofuginone. Bioorg Med Chem. 2014 Apr 1;22(7):1993-2004.