CAS NO: | 61177-44-4 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
Cas No. | 61177-44-4 |
别名 | 克拉维酸锂 |
Canonical SMILES | O=C([C@@H](/C(O[C@]1([H])C2)=C/CO)N1C2=O)O[Li] |
分子式 | C8H8LiNO5 |
分子量 | 205.09 |
溶解度 | Water: 50 mg/mL (243.80 mM); DMSO: 5 mg/mL (24.38 mM; ultrasonic and warming and heat to 80℃) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Clavulanate lithium is a potent β-lactamase inhibitor and acts as an antibiotic[1][2]. Clavulanate lithium has weak antibacterial activity against most organisms when administered alone, but given in combination with beta-lactam antibiotics prevents antibiotic inactivation by microbial lactamase[1].Clavulanate lithium (0.25, 0.5 mg/L) causes a relatively slow inhibition of growth, and a higher concentration (1 mg/L) is only marginally more effective than 0.5 mg/L [2]. Cell Viability Assay[2] Cell Line: L. pneumophila NCTC 1119 [1]. Reading C, et al. Clavulanic Acid: a Beta-Lactamase-Inhibiting Beta-Lactam from Streptomyces clavuligerus. Antimicrob Agents Chemother. 1977 May; 11(5): 852-857. [2]. Stokes DH, et al. Bactericidal effects of amoxycillin/clavulanic acid against intracellular Legionella pneumophila in tissue culture studies. J Antimicrob Chemother. 1989 Apr;23(4):547-56. |