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Clavulanate lithium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Clavulanate lithium图片
CAS NO:61177-44-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Clavulanate lithium 是一种高效的 β-lactamase 抑制剂,可作为抗生素。
Cas No.61177-44-4
别名克拉维酸锂
Canonical SMILESO=C([C@@H](/C(O[C@]1([H])C2)=C/CO)N1C2=O)O[Li]
分子式C8H8LiNO5
分子量205.09
溶解度Water: 50 mg/mL (243.80 mM); DMSO: 5 mg/mL (24.38 mM; ultrasonic and warming and heat to 80℃)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Clavulanate lithium is a potent β-lactamase inhibitor and acts as an antibiotic[1][2].

Clavulanate lithium has weak antibacterial activity against most organisms when administered alone, but given in combination with beta-lactam antibiotics prevents antibiotic inactivation by microbial lactamase[1].Clavulanate lithium (0.25, 0.5 mg/L) causes a relatively slow inhibition of growth, and a higher concentration (1 mg/L) is only marginally more effective than 0.5 mg/L [2]. Cell Viability Assay[2] Cell Line: L. pneumophila NCTC 1119

[1]. Reading C, et al. Clavulanic Acid: a Beta-Lactamase-Inhibiting Beta-Lactam from Streptomyces clavuligerus. Antimicrob Agents Chemother. 1977 May; 11(5): 852-857. [2]. Stokes DH, et al. Bactericidal effects of amoxycillin/clavulanic acid against intracellular Legionella pneumophila in tissue culture studies. J Antimicrob Chemother. 1989 Apr;23(4):547-56.