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8-Geranyloxypsoralen
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
8-Geranyloxypsoralen图片
CAS NO:7437-55-0
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
8-Geranyloxypsoralen 是从葡萄柚中分离出的一种呋喃香豆素,能作为 P450 3A4 (CYP3A4) 的有效抑制剂,其 IC50 值为 3.93 μM。
Cas No.7437-55-0
别名8-香叶草氧基补骨脂素
Canonical SMILESO=C1C=CC2=CC3=C(OC=C3)C(OC/C=C(C)/CC/C=C(C)/C)=C2O1
分子式C21H22O4
分子量338.4
溶解度Soluble in DMSO
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC50 of 3.93 μM[1]. IC50: 3.93 μM (P450 3A4)[1]

[1]. Row EC, et al. Synthesis of 8-geranyloxypsoralen analogues and their evaluation as inhibitors of CYP3A4. Bioorg Med Chem. 2006 Jun 1;14(11):3865-71.