Adipostatin A (Adipostatin A) 是一种 3-磷酸甘油脱氢酶 (GPDH) 抑制剂，IC50 为 4.1 μM.
| Cas No. | 3158-56-3 |
| 别名 | 5-十五烷基-1,3-苯二酚,Adipostatin A |
| Canonical SMILES | OC1=CC(O)=CC(CCCCCCCCCCCCCCC)=C1 |
| 分子式 | C21H36O2 |
| 分子量 | 320.5 |
| 溶解度 | DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Adipostatin A is an inhibitor of glycerol-3-phosphate dehydrogenase (GPDH; IC50 = 4.1 µM). It prevents triglyceride accumulation in 3T3-L1 cells when applied at 5-7.5 µM. Adipostatin A is cytotoxic against fibroblast carcinoma KB cell lines with an IC50 value of 10.6 µM. It also shows larvicidal activity (LC90 = 10.22 ppm) against A. aegypti. |
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