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Chaetoglobosin A
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Chaetoglobosin A图片
CAS NO:50335-03-0
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
Chaetoglobosin A 是青霉提取物中的活性成分，是细胞松弛素家族的成员。
Cas No.50335-03-0
别名球毛壳菌素 A
Canonical SMILESC/C([C@@H](O)C(/C=C/C1=O)=O)=C/[C@@H](C)C/C=C/[C@]2([H])[C@]1(C(N[C@H]3CC4=CNC5=C4C=CC=C5)=O)[C@@]3([H])[C@H](C)[C@]6(C)[C@H]2O6
分子式C32H36N2O5
分子量528.6
溶解度Methanol: Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Chaetoglobosin A, the active principle within the extract of Penicillium aquamarinium, is a member of the cytochalasan family. Chaetoglobosin A preferentially induces apoptosis. Chaetoglobosin A targets filamentous actin in CLL cells and thereby induces cell-cycle arrest and inhibits membrane ruffling and cell migration[1].

References:
[1]. Knudsen PB, et al. Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. Leukemia. 2014 Jun;28(6):1289-98.