脱氧胆酸(胆酸)钠水合物是一种胆汁酸,是肠道代谢的副产物,可激活 G 蛋白偶联胆汁酸受体 TGR5。
Cas No. | 145224-92-6 |
别名 | 一水脱氧胆酸钠,Cholanoic Acid sodium hydrate; Desoxycholic acid sodium hydrate |
Canonical SMILES | O[C@@H]1CC[C@@]2(C)[C@@](CC[C@]3([H])[C@]2([H])C[C@H](O)[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCC([O-])=O)([H])C1.[Na+].O |
分子式 | C24H39O4•Na [H2O] |
分子量 | 432.6 |
溶解度 | DMF: 5 mg/ml,DMSO: 10 mg/ml,Ethanol: 15 mg/ml,PBS (pH 7.2): 1 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Deoxycholic Acid (DCA) is a secondary bile acid produced from cholic acid by bacterial action in the colon. It is usually conjugated with glycine or taurine and acts as a detergent in the emulsification of fats for intestinal absorption. Elevated levels of DCA are strongly associated with the development of colon cancer. |