鹅去氧胆酸（钠盐）（鹅去氧胆酰甘氨酸钠盐）是一种胆汁酸，由鹅去氧胆酸盐和甘氨酸在肝脏中形成。它作为清洁剂溶解脂肪以供吸收，并且本身被吸收。 Glycochenodeoxycholic Acid (sodium salt) (鹅脱氧胆酰甘氨酸钠盐) 诱导肝细胞凋亡。
| Cas No. | 16564-43-5 |
| 别名 | 甘氨鹅脱氧胆酸钠; Chenodeoxycholylglycine sodium salt; Sodium glycochenodeoxycholate |
| Canonical SMILES | O[C@@H]1CC[C@@]2(C)[C@@](C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCC(NCC([O-])=O)=O)([H])C1.[Na+] |
| 分子式 | C26H42NO5•Na |
| 分子量 | 471.6 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Glycochenodeoxycholic acid (GCDCA) is a glycine-conjugated form of the primary bile acid chenodeoxycholic acid. It acts as a biosurfactant to solubilize lipids for absorption and is itself absorbed. GCDCA functions as a choleretic, increasing the volume of bile secreted from the liver, and a cholagogue, promoting the discharge of bile from the digestive system. GCDCA has been used to demonstrate a role for bile acids in promoting colorectal carcinogenesis and to inhibit calcium hydroxyapatite precipitation to study the pathogenesis of black pigment gallstones. |
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