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Nivalenol
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Nivalenol图片
CAS NO:23282-20-4
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
雪腐镰刀菌属禾谷镰刀菌产生的 B 型单端孢霉烯类毒素，是一种存在于农产品中的真菌代谢物。
Cas No.23282-20-4
别名雪腐镰刀菌烯醇
Canonical SMILESCC1=C[C@]2([H])[C@]([C@]3(C)[C@@]4(OC4)[C@]([C@H](O)[C@H]3O)([H])O2)(CO)[C@H](O)C1=O
分子式C15H20O7
分子量312.3
溶解度DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum, is a fungal metabolite present in agricultural product[1]. Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect[2].

References:
[1]. Bryla M, et al. Natural Occurrence of Nivalenol, Deoxynivalenol, and Deoxynivalenol-3-Glucoside in Polish Winter Wheat. Toxins (Basel). 2018 Feb 13;10(2).
[2]. Aupanun S, et al. Individual and combined mycotoxins deoxynivalenol, nivalenol, and fusarenon-X induced apoptosis in lymphoid tissues of mice after oral exposure. Toxicon. 2019 Jul;165:83-94.