CAS NO: | 14348-21-1 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Cas No. | 14348-21-1 |
别名 | 蛇床素 |
Canonical SMILES | O=C1C=CC2=C(OC/C=C(C)/C)C3=C(OC=C3)C(OC/C=C(C)/C)=C2O1 |
分子式 | C21H22O5 |
分子量 | 354.4 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Cnidicin is a coumarin from the root of Angelica koreana, and inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells[1]. Cnidicin shows a significant inhibition upon the release of beta-hexosaminidase from the cultured RBL-2H3 cells in a dose dependent manner (IC50= 25 μM) and upon the nitric oxide production from the activated RAW264.7 cells (IC50=7.5 μM)[1]. [1]. Ryu SY, et al. Cnidicin, a coumarin, from the root of Angelica koreana, inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells. Planta Med. 2001 Mar;67(2):172-4. |