CAS NO: | 371935-74-9 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
CAS: | 371935-74-9 |
分子式: | C19H16N4O3 |
分子量: | 348.36 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | p110α8 nM (IC50);p110β88 nM (IC50);p110δ48 nM (IC50);p110γ150 nM (IC50);PI3KC2β26 nM (IC50);PI3KC2α1 μM (IC50);hsVPS342.3 μM (IC50);mTORC120 nM (IC50);mTORC283 nM (IC50);DNA-PK2 nM |
描述: | PI-103 is a potent PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 also inhibits DNA-PK with an IC50 of 2 |