您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Boc-NH-PEG2-C2-amido-C4-acid
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Boc-NH-PEG2-C2-amido-C4-acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Boc-NH-PEG2-C2-amido-C4-acid图片
CAS NO:1310327-20-8
包装与价格:
包装价格(元)
100mg电议
250mg电议
1g电议

产品介绍
Boc-NH-PEG2-C2-amido-C4-acid (PROTAC Linker 30) 是一种 PROTAC linker,属于 PEG 类。Boc-NH-PEG2-C2-amido-C4-acid 可用于合成 PROTAC 分子。
Cas No.1310327-20-8
别名PROTAC Linker 30
分子式C17H32N2O7
分子量376.45
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Boc-NH-PEG2-C2-amido-C4-acid (PROTAC Linker 30) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Targ. J Med Chem. 2019 Aug 21.