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Amino-PEG6-amine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Amino-PEG6-amine图片
CAS NO:76927-70-3
包装与价格:
包装价格(元)
100mg电议
250mg电议
1g电议
5g电议

产品介绍
Amino-PEG6-amine是一种 PROTAC linker (6 个单元),属于 PEG 类。Amino-PEG6-amine可用于合成一系列 PROTAC 分子。
Cas No.76927-70-3
分子式C14H32N2O6
分子量324.41
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Amino-PEG6-amine is a PEG-based (6 units) PROTAC linker can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Shan M, et al. Nonsteroidal bivalent estrogen ligands: an application of the bivalent concept to the estrogen receptor. ACS Chem Biol. 2013 Apr 19;8(4):707-15.