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Radafaxine hydrochloride(GW-353162A)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Radafaxine hydrochloride(GW-353162A)图片
CAS NO:106083-71-0
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议

产品介绍
Radafaxine hydrochloride (GW-353162A) (GW-353162A) 是一种 DAT(多巴胺转运蛋白)和 NET(去甲肾上腺素转运蛋白)转运蛋白抑制剂和 nAChR 家族调节剂。
Cas No.106083-71-0
别名盐酸安非他酮吗啉代杂质,GW-353162A; BW-306U
Canonical SMILESO[C@]1(C2=CC=CC(Cl)=C2)[C@H](C)NC(C)(C)CO1.[H]Cl
分子式C13H19Cl2NO2
分子量292.2
溶解度DMSO : ≥ 38 mg/mL (130.05 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Radafaxine Hcl(BW-306U; GW-353162A) is a potent metabolite of bupropion; selective for inhibiting the reuptake of norepinephrine over dopamine; DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator.

[1]. Xu H, et al. Stereoselective analysis of hydroxybupropion and application to drug interaction studies. Chirality. 2007 Mar;19(3):163-70. [2]. Bondarev ML, et al. Behavioral and biochemical investigations of bupropion metabolites. Eur J Pharmacol. 2003 Aug 1;474(1):85-93.