CAS NO: | 94-63-3 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
25mg | 电议 |
100mg | 电议 |
250mg | 电议 |
Cas No. | 94-63-3 |
别名 | 碘解磷定 |
Canonical SMILES | C[N+]1=CC=CC=C1/C=N/O.[I-] |
分子式 | C7H9IN2O |
分子量 | 264.06 |
溶解度 | DMSO: 250 mg/mL (946.75 mM) |
储存条件 | Store at -20°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Pralidoxime iodide is a reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent, which inhibits AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning[1][2]. [1]. Cadieux CL, et al. Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents. Chem Biol Interact. 2016;259(Pt B):133‐141. [2]. Eyer P, Buckley N. Pralidoxime for organophosphate poisoning. Lancet. 2006;368(9553):2110‐2111. [3]. HouzÉ P, et al. High Dose of Pralidoxime Reverses Paraoxon-Induced Respiratory Toxicity in Mice. Turk J Anaesthesiol Reanim. 2018;46(2):131‐138. |