CAS NO: | 946128-88-7 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
CAS: | 946128-88-7 |
分子式: | C21H18FN5O5S |
分子量: | 471.46 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 160 nM (MEK), 8.2 nM (Braf(V600E)), 190 nM (Braf), 56 nM (CRAF)[1] |
描述: | Ro 5126766 is a first-in-class dual MEK/RAF inhibitor that allosterically inhibits BRAFV600E, CRAF, MEK, and BRAF (IC50: 8.2, 56, 160 nM, and 190 nM, respectively). |