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Cangrelor(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cangrelor(sodium salt)图片
CAS NO:163706-36-3
包装与价格:
包装价格(元)
10mM (in 1mL Water)电议
5mg电议
10mg电议
50mg电议

产品介绍
Cangrelor(钠盐)是一种三磷酸腺苷类似物,是一种可逆的选择性血小板 P2Y12 拮抗剂,具有迅速而有效的抗血小板作用。
Cas No.163706-36-3
别名坎格雷洛四钠盐,AR-C69931MX tetrasodium
Canonical SMILESO[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=C(SCCC(F)(F)F)N=C3NCCSC)O[C@@H]1COP(OP(C(Cl)(Cl)P([O-])([O-])=O)([O-])=O)([O-])=O.[Na+].[Na+].[Na+].[Na+]
分子式C17H21Cl2F3N5O12P3S2•4Na
分子量864.3
溶解度Water: Soluble
储存条件4°C, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cangrelor is an ATP analog that inhibits platelet aggregation (IC50 = 0.4 nM). It is a reversible competitive antagonist of the platelet purinergic P2Y12 receptor. Pretreatment with cangrelor significantly reduces blood clotting induced by ADP in a mouse model of pulmonary thromboembolism. Formulations containing cangrelor have been used to prevent blood clotting in at-risk patients.