您好，欢迎来到试剂仪器网！ [登录] [免费注册]
试剂仪器网
发布求购
位置：首页 > 产品库 > [Des-Arg9]-Bradykinin
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
[Des-Arg9]-Bradykinin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
[Des-Arg9]-Bradykinin图片
CAS NO:15958-92-6
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
[Des-Arg9]-Bradykinin 是一种Bradykinin (B1) 受体激动剂，对 B1 受体选择性比B2 受体高。
Cas No.15958-92-6
别名[Des-Arg9]-缓激肽
分子式C44H61N11O10
分子量904.02
溶解度DMF: 15mg/mL,DMSO: 15mg/mL,Ethanol: 10mg/mL,PBS (pH 7.2): 10mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors.

The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively[1].

References:
[1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.