产品名称: | 荷叶碱 |
CAS: | 475-83-2 |
分子式: | C19H21NO2 |
分子量: | 295.38 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years;4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Neurological Disease |
Target: | IC50: 131 nM (5-HT2C receptor), 150 nM (5-HT7 receptor), 478 nM (5-HT2A receptor), 1 μM (5-HT2B receptor)[1]EC50: 64 nM (D2 receptor), 2.6 μM (D5 receptor), 700 nM (5-HT6 receptor),3.2 μM (5-HT1A rec |
描述: | Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and |