CAS NO: | 229005-80-5 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
CAS: | 229005-80-5 |
分子式: | C33H39ClN2O2 |
分子量: | 531.13 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Infection/Inflammation/Immunology |
Target: | Ki: 1.1 nM (CCR5)[1]EC50: 1.2 nM (R5 HIV-1, in MAGI-CCR5 cells)[1]EC90: 5.7 nM (R5 HIV-1, in MAGI-CCR5 cells)[1]CXCR[2] |
描述: | TAK-779 is a potent and selective nonpeptide antagonist of CCR5 and CXCR3, with a Ki of 1.1 nM for CCR5, and effectively and selectively inhibits R5 HIV-1, with EC50 and EC90 of 1.2 nM and 5.7 nM, res |