| CAS： | 125314-64-9 |
| 分子式： | C25H23N5O2S |
| 分子量： | 457.55 |
| 纯度： | ≥98% |
| 溶解性： | 10 mM in DMSO |
| 存储： | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域： | Neurological Disease/Cardiovascular Disease |
| Target： | IC50: 5 nM (PKCα), 24 nM (PKCβI), 14 nM (PKCβII), 27 nM (PKCγ), 24 nM (PKCε), 23 nM (Rat brain PKC)[1], 3 nM (MAPKAP-K1b), 8 nM (MSK1), 15 nM (S6K1), 38 nM (GSK3β)[2] |
| 描述： | Ro 31-8220 is a potent PKC inhibitor, with IC50 of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, M |
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