CAS NO: | 457081-03-7 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
产品名称: | 吡啶酮6 |
CAS: | 457081-03-7 |
分子式: | C18H16FN3O |
分子量: | 309.34 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | JAK2, 1 nM (IC50); Tyk2, 1 nM (IC50); JAK3, 5 nM (IC50); Murine; JAK1, 15 nM (IC50) |
描述: | Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC50s of 1 nM for JAK2 and TYK2, 5 nM for JAK3, and 15 nM for JAK1, while displaying significantly weaker affinit |