CAS NO: | 880813-36-5 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
CAS: | 880813-36-5 |
分子式: | C16H18N2 |
分子量: | 238.33 |
纯度: | >98% |
溶解性: | H2O : < 0.1 mg/mL (insoluble); DMSO : 130 mg/mL (545.46 mM; Need ultrasonic) |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | Kd: 167 μM (p53-Y220C)[1], 150 μM (p53Y220C, in Ln229 cells) |
描述: | PhiKan 083 is a carbazole derivative, which binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 μM, and a relative binding affinity (Kd) of 150 μM in Ln229 cells. |