| CAS： | 599179-03-0 |
| 分子式： | C32H42F3N5O6 |
| 分子量： | 649.70 |
| 纯度： | ≥98% |
| 溶解性： | DMSO |
| 存储： | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| Target： | Ki: 2.5 nM (CCR5)[1]IC90: 3.3 nM (HIV JrFL, in PBMC cells), 2.8 nM (HIV ADA-M, in PBMC cells), 1.8 nM (HIV 301657, in PBMC cells), 4.9 nM (HIV JV1083, in PBMC cells) and 10 nM (HIV RU 570, in PBMC ce |
| 描述： | Vicriviroc maleate is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5, with a Ki of 2.5 nM, and also inhibits HIV-1 in PBMC cells, with IC90s of 3.3 nM (JrFL), 2.8 nM (ADA |
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