| CAS NO: | 4548-34-9 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| Cas No. | 4548-34-9 |
| 别名 | (1S,2R)-2-苯基-环丙胺盐酸盐,(1S,2R)-SKF 385 hydrochloride |
| 化学名 | (1S,2R)-2-phenylcyclopropan-1-amine;hydrochloride |
| Canonical SMILES | C1C(C1N)C2=CC=CC=C2.Cl |
| 分子式 | C9H11N.HCl |
| 分子量 | 169.65 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Tranylcypromine, also known as 2-PCPA, is a monoamine oxidase inhibitor (MAOI) that irreversibly inhibits MAO A and MAO B with the inhibition constant Ki values of 101.9 μM and 16 μM and the half maximal inhibition concentration IC50 values of 2.3 μM and 0.95 μM respectively [1]. Tranylcypromine has also been found to potently and irreversibly inhibit histone demethylase lysine-specific demethylase 1 (LSD1), which is an amine oxidase homologue of MAO sharing similarities in the catalytic site with MAO A and B, in a time dependent and mechanism based manner with Ki and IC50 values of 242 μM and 20.7 μM respectively [1]. Reference References: |
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