CAS NO: | 916489-36-6 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
CAS: | 916489-36-6 |
分子式: | C20H19ClN4O2S |
分子量: | 414.91 |
纯度: | >98% |
溶解性: | Ethanol |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Infection;Inflammation/Immunology |
Target: | IC50: 30 nM (BRD4-BD1), 46 nM (BRD4-BD2), 32.7 μM (CBP BRD) |
描述: | MS417 is a BET-specific BRD4 inhibitor, binds to BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively, with weak selectivity at CBP BRD (IC50, 32.7 μM). |