Petromurin C 是一种双吲哚基苯类化合物，从 Petromycesmuricatus 的 ascostromata 中分离出来。 Petromurin C 在 FLT3-ITD 阳性 AML 中诱导保护性自噬和细胞凋亡。
| Cas No. | 194608-29-2 |
| Canonical SMILES | COC1=C(C2=CNC3=C2C=C(O)C=C3)C(OC)=C(OC)C(C4=CNC5=C4C=CC=C5)=C1OC |
| 分子式 | C26H24N2O5 |
| 分子量 | 444.5 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Petromurin C is a bis-indolyl benzenoid fungal metabolite originally isolated from the ascostromata of P. muricatus. It is cytotoxic to NS-1 mouse myeloma cells (IC50 = 33 μg/ml) and has activity against T. foetus in vitro (IC50 = 100 μg/ml). |
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