植物鞘氨醇是一种磷脂，具有抗癌活性。植物鞘氨醇通过激活 caspase 8 和癌细胞中的 Bax 易位诱导细胞凋亡。
| Cas No. | 554-62-1 |
| 别名 | 植物鞘氨醇 |
| Canonical SMILES | O[C@@H]([C@@H](O)[C@@H](N)CO)CCCCCCCCCCCCCC |
| 分子式 | C18H39NO3 |
| 分子量 | 317.5 |
| 溶解度 | DMF: 10 mg/ml,DMSO: 2 mg/ml,Ethanol: miscible |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Phytosphingosine is a sphingolipid with a hydroxyl group at the C4 position that is found mainly in fungi and plants but also in animals, including humans. It is metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid as an intermediate. Phytosphingosine dose-dependently induces cell death of CHO cells and inhibits carbachol-induced activation of phospholipase D (PLD) in CHO cells transfected with C. elegans muscarinic acetylcholine receptors. It is essential in the heat stress response in S. cerevisiae. |
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