Pyridoxatin 是一种微生物来源的自由基清除剂。
| Cas No. | 135529-30-5 |
| Canonical SMILES | C[C@H]1C[C@@H](C=C)[C@H](C2=C(O)C=CN(O)C2=O)[C@@H](C)C1 |
| 分子式 | C15H21NO3 |
| 分子量 | 263.3 |
| 溶解度 | DMSO: soluble,Methanol: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Pyridoxatin is a fungal metabolite originally isolated from Acremonium with diverse biological activities. It inhibits production of thiobarbituric acid reactive substance (TBARS) in vitro (IC50 = 0.55 μg/ml). Pyridoxatin inhibits hemolysis induced by the free radical generator AAPH in rat erythrocytes (IC50 = 1.95 μg/ml). It is active against C. albicans (MIC = 1.64 μg/ml). Pyridoxatin is cytotoxic in a panel of 21 cancer cell lines (EC50s = 0.10-7.04 μg/ml). It also inhibits gelatinase A (IC50 = 15.2 μM). |
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