CAS NO: | 1339928-25-4 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
CAS: | 1339928-25-4 |
分子式: | C23H24N8O4S |
分子量: | 508.55 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | PI3Kα, 19 nM (IC50); PI3Kβ, 54 nM (IC50); PI3Kδ, 39 nM (IC50); PI3Kγ, 311 nM (IC50); HDAC1, 1.7 nM (IC50); HDAC2, 5 nM (IC50); HDAC3, 1.8 nM (IC50); HDAC4, 409 nM (IC50); HDAC5, 674 nM (IC50); HDAC6, |
描述: | Fimepinostat (CUDC-907) potently inhibits class I PI3Ks as well as classes I and II HDAC enzymes with an IC50 of 19/54/39 nM and 1.7/5.0/1.8/2.8 nM for PI3Kα/PI3Kβ/PI3Kδ and HDAC1/HDAC2/HDAC3/HDAC10 , |