| CAS NO: | 4176-97-0 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
14-Deoxyandrographolide 是 Andrographis paniculata 的生物活性成分，具有保护肝脏的作用。14-Deoxyandrographolide 通过诱导 TNFRSF1A 的释放，逐渐使肝细胞对 TNF-α 介导的凋亡脱敏。
| Cas No. | 4176-97-0 |
| 别名 | 14-去氧穿心莲内酯 |
| Canonical SMILES | O=C1OCC=C1CC[C@@H]2C(CC[C@]3([H])[C@](C)(CO)[C@H](O)CC[C@@]23C)=C |
| 分子式 | C20H30O4 |
| 分子量 | 334.45 |
| 溶解度 | Acetonitrile: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 14-Deoxyandrographolide, a bioactive compound of Andrographis paniculata, has hepatoprotective efficacy. 14-Deoxyandrographolide desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release[1]. [1]. Roy DN, et al. 14-Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor-alpha-induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway. Br J Pharmacol. 2010 Aug;160(7):1823-43. |
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