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3-Dehydrotrametenolic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
3-Dehydrotrametenolic acid图片
CAS NO:29220-16-4
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
3-?Dehydrotrametenolic acid,分离于茯苓菌核,是一种乳酸脱氢酶 (LDH) 抑制剂。3-?Dehydrotrametenolic acid 促进体外脂肪细胞分化,在体内起胰岛素增敏剂的作用。3-?Dehydrotrametenolic acid 诱导细胞凋亡,具有抗癌活性。
Cas No.29220-16-4
别名3-氢化去氢松苓酸
Canonical SMILESCC1(C)[C@@H](O)CC[C@]2(C)C3=CC[C@]4(C)[C@@H]([C@H](C(O)=O)CC/C=C(C)\C)CC[C@](C)4C3=CC[C@@]12[H]
分子式C30H46O3
分子量454.68
溶解度Soluble in DMSO
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3-?Dehydrotrametenolic acid, isolated from the sclerotium of Poria cocos, is a lactate dehydrogenase (LDH) inhibitor. 3-?Dehydrotrametenolic acid promotes adipocyte differentiation in vitro and acts as an insulin sensitizer in vivo. 3-?Dehydrotrametenolic acid induces apoptosis and has anticancer activity[1][2]. Lactate dehydrogenase [1]

[1]. De Nicola GR, et al. Novel gram-scale production of enantiopure R-sulforaphane from Tuscan black kale seeds. Molecules. 2014 May 27;19(6):6975-86. [2]. Abdull Razis AF, et al. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Int J Cancer. 2011 Jun 15;128(12):2775-82.