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GS-704277
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GS-704277图片
CAS NO:1911579-04-8
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
GS-704277是Remdesivir的丙氨酸代谢产物。Remdesivir是一种具有抗病毒活性的核苷类似物,在体外对SARS-CoV-2(COVID-19)感染具有很高的抑制作用。
Cas No.1911579-04-8
Canonical SMILESN#C[C@@]1(C2=CC=C3N2N=CN=C3N)O[C@@H]([C@H]([C@H]1O)O)COP(N[C@@H](C)C(O)=O)(O)=O
分子式C15H19N6O8P
分子量442.32
溶解度DMSO: soluble
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

GS-704277 is an alanine metabolite of Remdesivir. Remdesivir, a nucleoside analogue with effective antiviral activity, is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[1][2].

[1]. Eastman RT, et al. Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19 [published correction appears in ACS Cent Sci. 2020 Jun 24;6(6):1009]. ACS Cent Sci. 2020;6(5):672-683. [2]. Wang M, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 Mar;30(3):269-271.