CAS NO: | 1357349-91-7 |
包装: | 5mg |
市场价: | 2830元 |
CAS: | 1357349-91-7 |
分子式: | C16H15N5 |
分子量: | 277.32 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 8 nM (RET) |
描述: | SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC50 of 8 nM. SPP-86 inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling. |