| 产品名称： | 卡博替尼苹果酸盐 |
| CAS： | 1140909-48-3 |
| 分子式： | C32H30FN3O10 |
| 分子量： | 635.59 |
| 纯度： | ≥98% |
| 溶解性： | DMSO: ≥ 23 mg/mL |
| 存储： | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域： | Cancer |
| Target： | IC50: 0.035 nM (VEGFR-2 (KDR)), 1.3 nM (c-Met), 4 nM (Ret), 4.6 nM (Kit), 12 nM (Flt-1), 11.3 nM (Flt-2), 6 nM (Flt-3), 14.3 nM (Tie2), 7 nM (AXL) |
| 描述： | Cabozantinib S-malate is a potent VEGFR2 inhibitor with IC50 of 0.035 nM, and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM a |
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![Cabozantinib S-malate(XL184 S-malate BMS-907351 S-malate) [CAS 1140909-48-3]图片](http://www.cnreagent.com/data/daily/2023/03/22/114211_158020_umcs_1046879.png)