CAS NO: | 802539-81-7 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
CAS: | 802539-81-7 |
分子式: | C25H32N8O |
分子量: | 460.57 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 45 nM (cyclin A/CDK2), 150 nM (cyclin H/CDK7), 160 nM (cyclin D1/CDK4), 363 nM (cyclin E/CDK2), 398 nM (cyclin B/CDK1)[1], 53 nM (TRKA)[2] |
描述: | PHA-848125 is a potent, dual inhibitor of CDK and Tropomyosin receptor kinase (TRK), with IC50 of 45, 150, 160, 363, 398 nM and 53 nM for cyclin A/CDK2, cyclin H/CDK7, cyclin D1/CDK4, cyclin E/CDK2, c |