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caudatin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
caudatin图片
CAS NO:38395-02-7
包装:20mg
市场价:2195元

产品介绍
Caudatin 是一种在 Cynanchum auriculatum 中发现的甾体化合物,可导致细胞周期停滞并诱导细胞凋亡,具有抗癌和抗血管生成特性。
Cas No.38395-02-7
别名告达亭苷元
化学名(E)-(3S,8S,9R,10R,12R,13S,14R,17R)-17-acetyl-3,8,14,17-tetrahydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-12-yl 3,4-dimethylpent-2-enoate
Canonical SMILESCC(/C(C)=C([H])/C(O[C@]([C@]12C)([H])C[C@]3([H])[C@]4(CC[C@@](O)([H])CC4=CC[C@@]3(O)[C@@]2(O)CC[C@]1(O)C(C)=O)C)=O)C
分子式C28H42O7
分子量490.63
溶解度≥ 49.1mg/mL in DMSO
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Caudatin is a steroidal cmpound found in Cynanchum auriculatum, causes cell cycle arrest and induces apoptosis, with anti-cancer and antiangiogenic properties[1].

References:
[1]. Wang X, et al. Antiangiogenic properties of caudatin in vitro and in vivo by suppression of VEGF-VEGFR2-AKT/FAK signal axis. Mol Med Rep. 2017 Dec;16(6):8937-8943.