CAS NO: | 1140964-99-3 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
CAS: | 1140964-99-3 |
分子式: | C18H15N5O |
分子量: | 317.34 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 2.0 nM (PARP1), 1.0 nM (PARP2), ~50 nM (TNKS1), ~50 nM (TNKS2)[1] |
描述: | E7449 is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50 of 2.0, 1.0, ~50 and ~50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate. |