CAS NO: | 1645286-75-4 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
CAS: | 1645286-75-4 |
分子式: | C25H28N6O |
分子量: | 428.53 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 3 nM (TNKS1), 1 nM (TNKS2), 2.0 μM (PARP1), 0.5 μM (PARP2), >3 μM (PARP6)[1] |
描述: | AZ6102 is a potent dual TNKS1 and TNKS2 inhibitor, with IC50 of 3 nM and 1 nM, respectively, and alao has 100-fold selectivity against other PARP family enzymes, with IC50 of 2.0 μM, 0.5 μM, and >3 μM |