CAS NO: | 1223001-51-1 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
CAS: | 1223001-51-1 |
分子式: | C24H15F3N4O |
分子量: | 432.40 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | mTOR, 2.81 nM (IC50); mTORC1, mTORC2, DNA-PK, 0.5 nM (IC50); PI3K-C2α, 28.1 nM (IC50); PI3K-C2β, 24.5 nM (IC50); p110γ, 5.67 nM (IC50); hVps34, 8.58 nM (IC50); ΡΙ4Κβ, 18.3 nM (IC50); Autophagy PI3K, 2 |
描述: | Torin 2 is an mTOR inhibitor with EC50 of 0.25 nM for inhibiting cellular mTOR activity, and exhibits 800-fold selectivity over PI3K (EC50: 200 nM). |