Ald-CH2-PEG3-azide

立即咨询

Ald-CH2-PEG3-azide

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1002342-83-7

包装与价格：

产品介绍

Ald-CH2-PEG3-azide 是一种可降解 (cleavable) 的含 3 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。Ald-CH2-PEG3-azide 是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC 分子。

Cas No.	1002342-83-7
分子式	C₈H₁₅N₃O₄
分子量	217.22
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Ald-CH2-PEG3-azide is a cleavable 3 unit PEGADC linkerused in the synthesis of antibody-drug conjugates (ADCs). Ald-CH2-PEG3-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs^[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. [1]. Harold L. Kohn , et al. Acylhydrazone-based cleavable linkers. WO2010014236A2.