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BI-9627
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BI-9627图片
CAS NO:1204329-34-9
包装:5mg
市场价:1890元

产品介绍
BI-9627是一种钠氢交换异构体1(NHE1)抑制剂,EC50值为31nM.
Cas No.1204329-34-9
Canonical SMILESNC(NC(C1=CC=C(C2CCN(C(C)=O)CC2)C(C(F)(F)F)=C1)=O)=N
分子式C16H19F3N4O2
分子量356.34
溶解度DMF: 10mg/mL,DMSO: 20mg/mL,DMSO:PBS (pH 7.2) (1:7): 0.12mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

BI-9627 is a sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor with an EC50 of 31 nM[1]. EC50: 31 nM (Sodium-hydrogen exchanger isoform 1)[1]

[1]. Huber JD, et al. Identification of a potent sodium hydrogen exchanger isoform 1 (NHE1) inhibitor with a suitableprofile for chronic dosing and demonstrated cardioprotective effects in a preclinical model of myocardial infarction in the rat. J Med Chem. 2012 Aug 23;55(16):7114-40.