PF 477736(PF 00477736)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
产品介绍
CAS: | 952021-60-2 |
分子式: | C22H25N7O2 |
分子量: | 419.48 |
纯度: | ≥98% |
溶解性: | 10 mM in DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | Ki: 0.49 nM (Chk1), 47 nM (Chk2), 9.9 μM (CDK1)[1][2] |
描述: | PF 477736 is a potent, selective ATP-competitive inhibitor of Chk1, with a Ki of 0.49 nM, 100-fold selectivity versus Chk2 (Ki, 47 nM). |