CAS NO: | 1229582-33-5 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
CAS: | 1229582-33-5 |
分子式: | C27H27N5 |
分子量: | 421.54 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Neurological Disease |
Target: | MLK3m 14 nM (IC50); LRRK2, 11 nM (IC50); FLT3, 4 nM (IC50); FLT1, 39 nM (IC50); ABL1 (T315I), 3 nM (IC50); ABL1, 6.8 nM (IC50) |
描述: | URMC-099 is an orally bioavailable and potent mixed lineage kinase type 3 (MLK3) (IC50=14 nM) inhibitor with with excellent blood-brain barrier penetration properties. |