| CAS： | 1229236-86-5 |
| 分子式： | C23H25ClFN7O |
| 分子量： | 469.94 |
| 纯度： | >98% |
| 溶解性： | DMSO |
| 存储： | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域： | Cancer |
| Target： | JAK2, 3 nM (IC50); FGFR2, 32 nM (IC50); Flt-4, 25 nM (IC50); Tyk2, 44 nM (IC50); JAK3, 48 nM (IC50); FGFR3, 106 nM (IC50); KDR, 109 nM (IC50); FLT3, 4 nM (IC50); TRKB, 95 nM (IC50); ALK, 138 nM (IC50) |
| 描述： | Gandotinib (LY2784544) is a potent JAK2 inhibitor with IC50 of 3 nM. Gandotinib (LY2784544) also inhibits FLT3, FLT4, FGFR2, TYK2, and TRKB with IC50 of 4, 25, 32, 44, and 95 nM. |
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