CAS NO: | 1626387-80-1 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
CAS: | 1626387-80-1 |
分子式: | C22H23ClFN5O3 |
分子量: | 459.90 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 0.3 nM (EGFR), 0.2 nM (EGFR(L858R)), 0.2 nM (EGFR(Exon 19 deletion))[1] |
描述: | AZD3759 is a potent, oral active, central nervous system-penetrant, EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.3, 0.2, and 0.2 nM for EGFRwt, EGFRL858R, and EGFRexon 19Del, respectively |