CAS NO: | 1421373-98-9 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
CAS: | 1421373-98-9 |
分子式: | C27H31N7O2 |
分子量: | 485.58 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 1 nM (EGFR(L858R/T790M)),1 nM (EGFR(L858R)),6 nM (EGFR(L861Q)),25 nM (EGFR),17 nM (ErbB4) |
描述: | AZ-5104 is an active, demethylated metabolite of AZD 9291. AZ-5104 is an EGFR inhibitor with IC50s of 1, 6, 1, 25 and 7 nM for EGFRL858R/T790M, EGFRL858R, EGFRL861Q, EGFR and ErbB4, respectively. |