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1-Hydroxy-ibuprofen
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
1-Hydroxy-ibuprofen图片
CAS NO:53949-53-4
包装:1mg
市场价:900元

产品介绍
1-HydroxyIbuprofen是Ibuprofen的活性代谢物。Ibuprofen是 COX-1 和COX-2 的抑制剂,IC50 值分别为13μM和370μM,具有抗炎活性。
Cas No.53949-53-4
别名1-羟基异丁基苯基-1'-甲基丙酸
Canonical SMILESO=C(O)C(C)C1=CC=C(C(O)C(C)C)C=C1
分子式C13H18O3
分子量222.28
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

1-Hydroxy Ibuprofen is a metabolite of Ibuprofen in P. australis[1]. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1].

[1]. Yujie He, et al. Metabolism of Ibuprofen by Phragmites australis: Uptake and Phytodegradation. Environ Sci Technol. 2017 Apr 18;51(8):4576-4584. [2]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.