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3-O-Methyldopa
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
3-O-Methyldopa图片
CAS NO:300-48-1
包装与价格:
包装价格(元)
10mM (in 1mL Water)电议
1mg电议
5mg电议

产品介绍
3-O-Methyldopa(3-Methoxy-L-tyrosine)是一种由邻苯二酚-O-甲基转移酶(COMT)形成的L-DOPA代谢物。3-O-Methyldopa竞争性抑制L-DOPA和多巴胺(dopamine)的药效学。
Cas No.300-48-1
别名(S)-2-氨基-3-(4-羟基-3-甲氧苯基)丙酸,3-Methoxy-L-tyrosine; 3-O-Methyl-L-DOPA
Canonical SMILESN[C@@H](CC1=CC=C(O)C(OC)=C1)C(O)=O
分子式C10H13NO4
分子量211.21
溶解度Water: 16.67 mg/mL (78.93 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA and dopamine[1].

[1]. Masato Asanuma, et al. 3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of L-DOPA. BMC Neurosci. 2016 Jul 25;17(1):52.