CAS NO: | 1352066-68-2 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
CAS: | 1352066-68-2 |
分子式: | C28H35Cl2NO5S |
分子量: | 568.55 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 0.6 nM (p53-MDM2 interaction)[1]Kd: 0.045 nM (MDM2)[1] |
描述: | AMG 232 is an extremely potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC50 of 0.6 nM, and binds to MDM2 with a Kd of 0.045 nM. |