| CAS NO: | 58131-57-0 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 2mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| Molecular Weight (MW) | 279.25 |
|---|---|
| Formula | C11H13N5O4 |
| CAS No. | 58131-57-0 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO: 0.4 mg/mL (1.43 mM) |
| Water:<1 mg/mL (slightly soluble or insoluble) | |
| Ethanol: <1 mg/mL | |
| Synonyms | NSC-207895, NSC207895, XI-006, XI 006, XI006, NSC 207895, NSC179940, NSC-179940, NSC 179940 |
| In vitro | NSC-207895 decreases both the MDMX mRNA and protein in MCF-7 cells. NSC-207895 induces expression of p53 as well as well-characterized p53-target gene, p21 and MDM2, in a dose-dependent manner in MCF-7 cells. NSC-207895 extends the half-life of p53 from 20 to 30 minutes to more than 3 hours as revealed by cycloheximide chase assays in MCF-7 cells. |
|---|---|
| In vivo | |
| Formulation | |
| Dosages | |
| Administration | |
| Reference | [1] Wang H, et al. Mol Cancer Ther, 2011, 10(1), 69-79. |
 NSC-207895 is a DNA damaging agent. Molecular Systems Biology 6(1):451 December 2010 |
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